More info
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Background: |
Factor P is a 53,000 dalton cationic protein that circulates in blood in the form of dimers, trimers and tetramers. It binds rapidly to C3b on surfaces where complement has begun to activate. Factor P binds most avidly to C3b, Bb the alternative pathway C3/C5 convertase, but also binds to C3b and C3b,B complex with lower affinity. Its primary function is to stabilize the C3b, Bb complex allowing increased alternative pathway activation. |
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Storage: |
-70 C or below. Avoid freeze/thaw |
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Source: |
Normal human serum |
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Activity: Purity: |
>70% versus normal human serum standard >95% by SDS-PAGE |
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Molecular Weight: Size: |
53,000 Da (single chain) 100 µg/vial |
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Concentration: |
1.0 mg/mL |
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Buffer: |
10 mM sodium phosphate, 145 mM NaCl, pH 7.3 |
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Preservative: |
None, 0.22 µm filtered |