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Creatine Kinase Muscle Human ( CKM Human )
DescriptionHuman CKM produced in Human Cardiac Tissues having a molecular mass of 82 kDa and PI 5.0-7.5. It's the skeletal muscle specific creatine kinase and is elevated in case of strenuous exercise and in degenerative muscle disease.SourceHuman
Data sheet
| Formulation | The CKM protein solution is in 50mM Tris and 2mM DTT, pH 7.5 containing 50% Glycerol. |
| Purity | Greater than 50.0%. |
| Description | Human CKM produced in Human Cardiac Tissues having a molecular mass of 82 kDa and PI 5.0-7.5. Its the skeletal muscle specific creatine kinase and is elevated in case of strenuous exercise and in degenerative muscle disease. |
| Protein Background | The three isoenzymes (MM, MB, and BB) are found in muscle, cardiac and brain tissues. These recombinant proteins are ideal for calibrating diagnostic instruments and researching neuromuscular diseases. Creatine Kinases can be used for indications in many neuromuscular applications. These disorders include cardiac disease, mitochondrial disorders, inflammatory myopathies, myasthenia, polymyositis, McArdle''s disease, NMJ disorders, muscular dystrophy, ALS, hypo and hyperthyroid disorders, central core disease, acid maltase deficiency, myoglobinuria, rhabdomyolysis, motor neuron diseases, rheumatic diseases, and other that create elevated or reduced levels of Creatine Kinases. |
| Expression host | Human Cardiac Tissues |
| Synonyms | Creatine kinase M-type, EC 2.7.3.2, Creatine kinase M chain, M-CK, CKM, CKMM. |
| Reagent Appearance | Sterile Filtered clear solution. |
| Stability | CKM although stable at 14°C for 1 week, should be stored at 2°-8°C. |