Bovine Apolipoprotein A1 APOA1 ELISA Kit

Assay Range:125-4000 μg/ml

Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in plasma. Chylomicrons secreted from the intestinal enterocyte also contain apo A-I but it is quickly transferred to HDL in the bloodstream. The protein promotes fat efflux, including cholesterol, from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Apo A-I was also isolated as a prostacyclin (PGI2) stabilizing factor, and thus may have an anticlotting effect. Defects in the gene encoding it are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathicamyloidosis.

Product Citations:

1. Influence of Body Condition on Serum Metabolic Indicators of Lipid Mobilization and Oxidative Stress in Dairy Cows During the Transition Period

I Folnozic et al, Reproduction in Domestic Animals, DOI: 10.1111/rda.12608.

2. Paraoxonase-1 activity and lipid profile in dairy cows with subclinical and clinical mastitis, Kovacic M et al, Journal of Applied Animal Research, 10.1080/09712119.2018.1555090, 47, 1, (1-4), (2018).