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Human Scrub typhus IgM ELISA Kit

NR-R10008

$720.00

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Principle
Indirect ELISA: Antigen Coated Plate
 
Detection Range
Qualitative Positive; Negative control 
 
Size
96T
 
Assay time
120 min
 
Shelf Life
12 ~ 18 Months from the Manufacturing Date
 
Storage
Store at 2 - 8ºC. 
 
Sample 
Serum or Plasma
 
Detection Method
Chromogenic
 
 
Kit Components
 
 
 
1. One 96-well plate precoated with Scrub Typhus 
 
 
2. Assa diluent buffer: 12 mL x 1
 
 
3. HRP conjugated: 1 vial
 
 
4. Negative Control:1vial
 
 
5. Positive Control: 1 vial
 
 
6. 20 x Wash buffer: 1 vial
 
 
7. TMB substrate: 12 ml
 
 
8. TMB stop solution: 12 ml

 

Background

 

Scrub typhus or Bush typhus is a form of typhus caused by the intracellular parasite Orientia tsutsugamushi, a Gram-negative Î±-proteobacterium of family Rickettsiaceae. Although the disease is similar in presentation to other forms of typhus, its pathogen is not anymore included in genus Rickettsia with the typhus bacteria proper, but in Orientia. The disease is thus frequently classified separately from the other typhi. Symptoms include fever, headache, muscle pain, cough, and  gastrointestinal symptoms. More virulent strains of O. tsutsugamushi can cause hemorrhaging and intravascular coagulation. Morbilliform rash, eschar, splenomegaly and lymphadenopathies are typical signs.  Pneumonitis, encephalitis, and myocarditis occur in the late phase of illness. With therapy, the fever will break within 36 hours, but if left untreated, complications or death may occur.

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