Specificity |
reactive with Rat Jagged 1, reactivity with other related proteins not observed |
Assay Range |
125-8000 pg/mL |
Sensitivity |
12 pg/ml |
Size |
96 Tests |
Storage |
2-8℃ |
Background |
JAG1 is a protein associated with Alagille syndrome. JAG1 has also been designated as CD339 .The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. |
Sample type |
serum, plasma, cell culture supernatant |
Assay duration |
4 hours |
Assay format |
Sandwich |
Alternative Name of Analyte |
JAG1;AGS;AHD;AWS;CD339;HJ1;JAGL1 |