| Specificity |
reactive with Human Total IkB-alpha, reactivity with other related proteins not observed |
| Assay Range |
56-3600pg/ml |
| Sensitivity |
5.4 pg/ml |
| Size |
96 Tests |
| Storage |
2-8℃ |
| Background |
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. |
| Sample type |
serum, plasma, cell culture supernatant |
| Assay duration |
4 hours |
| Assay format |
Sandwich |
| Alternative Name of Analyte |
IKBA；MAD-3；NFKBI |
