| Storage |
SARS Mosaic protein is shipped at ambient temperature.Upon arrival, store at -20C. |
| Formulation |
25mM Tris-HCl, 0.4% sarcosyl, 0.25% Triton 100 and 50% glycerol. |
| Purity |
SARS Mosaic Protein is >95% pure as determined by 10% PAGE (coomassie staining). |
| Applications |
SARS Mosaic antigen is suitable for ELISA and Western blots, excellent antigen for detection of SARS with minimal specificity problems. |
| Description |
The E.Coli derived 37 kDa recombinant mosaic protein contains the C-terminal t section of the Spike protein 1051-1076, 1121-1154, 1162-1190 amino acids immunodominant regions. |
| Protein Background |
SARS Coronavirus is an enveloped virus containing three outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies. |
| Purification Method |
SARS Mosaic protein was purified by proprietary chromatographic technique. |
