| Formulation |
The GNG4 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol. |
| Purity |
Greater than 85% as determined by SDS-PAGE. |
| Description |
GNG4 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 95 amino acids (1-72) and having a molecular mass of 10.4 kDa. GNG4 is fused to a 23 amino acid His-tag at N-terminus. |
| Protein Background |
GNG4 belongs to a multigene family and is involved in defining the specificity of receptor-G protein interaction. In mammals, G protein alpha, beta and gamma polypeptides are encoded by no less than 16, 4 and 7 genes, respectively. It is a well-known fact that different G protein complexes expressed in different tissues carry structurally distinct members of the alpha beta and gamma subunits and that privileged connotation between members of subunit families rise G protein functional diversity. |
| Expression host |
Escherichia Coli. |
| Synonyms |
Guanine Nucleotide Binding Protein (G Protein) Gamma 4, Guanine Nucleotide-Binding Protein G(I)/G(S)/G(O) Subunit Gamma-4, GNGT4. |
| Reagent Appearance |
Sterile Filtered clear solution. |
| Stability |
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Amino acid sequence |
MGSSHHHHHH SSGLVPRGSH MGSMKEGMSN NSTTSISQAR KAVEQLKMEA CMDRVKVSQA AADLLAYCEA HVREDPLIIP VPASENPFRE KKFFC |
| Product Description |
Recognizes Hepatitis C virus. Specific to NS-3. |
