| Formulation |
CHRAC1 protein solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M urea and 10% glycerol. |
| Purity |
Greater than 90% as determined by SDS-PAGE. |
| Description |
CHRAC1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 154 amino acids (1-131 a.a.) and having a molecular mass of 17.1kDa. CHRAC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
| Protein Background |
Chromatin Accessibility Complex 1 (CHRAC1) is a histone-fold protein which interacts with further histone-fold proteins to bind DNA in a sequence-independent mode. These histone-fold protein dimers combine within larger enzymatic complexes for DNA replication, transcription, and packaging. |
| Expression host |
E.coli. |
| Synonyms |
CHARC1, CHARC15, CHRAC-1, CHRAC-15, CHRAC15, YCL1, Chromatin accessibility complex protein 1, Chromatin accessibility complex 15 kDa protein, DNA polymerase epsilon subunit p15. |
| Reagent Appearance |
Sterile Filtered colorless solution. |
| Stability |
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Amino acid sequence |
MGSSHHHHHH SSGLVPRGSH MGSMADVVVG KDKGGEQRLI SLPLSRIRVI MKSSPEVSSI NQEALVLTAK ATELFVQCLA TYSYRHGSGK EKKVLTYSDL ANTAQQSETF QFLADILPKK ILASKYLKML KEEKREEDEE NDNDNESDHD EADS. |
