| Formulation |
Each mg contains 1X PBS, 0.1% SDS and 1mM DTT. |
| Solubility |
It is recommended to reconstitute the lyophilized CD-4 (203-317)in sterile 18M-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions. |
| Applications |
Protein Assay. Antibody Production. Western Blotting. |
| Description |
CD-4 Human Recombinant His Tag protein encoding 203-317 amino acids. |
| Protein Background |
CD4, a single chain transmembrane glycoprotein, is found on a T cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. It is also present on 80% of thymocytes and at a lower level on monocytes. It is involved in recognition of antigen presented along with MHC class II by APCs. It serves as receptor for HIV. Antibody to CD4 recognizes T-helper cells required for recognition of class II antigens. It reacts with ~60% of peripheral blood E rosette-positive (E+) cells while showing negligible reactivity with E- cells, monocytes, granulocytes, EBV-transformed B cell lines, and mouse splenocytes. |
| Expression host |
Escherichia Coli. |
| Synonyms |
gp55, HLA-2, L3 / T4, Ly-4, T cell antigen T4/LEU3, T4, sCD4. |
| Reagent Appearance |
Sterile lyophilized powder. |
| Stability |
Store vial at -20oC to -80oC. When stored at the recommended temperature, this protein is stable for 12 months. Please avoid freeze-thaw cycles. |
